Title

Description

REF No

2125

Purpose

10% Formalin Buffered Neutral Fixative is used in histology and pathology laboratories to preserve tissue samples for long periods of time and to fix them for microscopic examination. It is especially ideal for: preserving biopsy and surgical tissue samples, preventing deterioration of morphology, providing fixation suitable for staining (H&E, Immunohistochemistry, etc.), and providing stabilization by cross-linking proteins and cellular components.

Ingredients

Formalin, phosphate buffers

Working Principle

Formaldehyde binds proteins within the tissue, hardening and protecting the tissue. The buffer system prevents acid formation, thus reducing tissue shrinkage compared to acid fixatives. It supports the protection of cell membranes and ensures that tissues are fixed as close to their natural structure as possible.

Warnings, Precautions, Recommendations

Danger. Causes severe skin burns and eye damage. May cause respiratory irritation. Suspected of causing cancer. Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if worn and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. If eye irritation persists: Get medical advice/attention.

Shelf Life

2 years

Storage Temperature

15/25°C

pH (at 25°C)

pH: 7,0 ±0,3.

Ordering and Packaging Information

Order No	Unit	Volume	Packaging Type	Quantity in a Box
442125000050	Piece	50 mL	50 ml, White Bottle with HDPE Dropper	20

Keywords

Formalin Buffered Neutral Fixative, Formalin Fixative